原创论文
2021-10-28
Disposable process equipment has seen dramatic growth in the past few years, as drug manufacturers adopt single-use systems to reduce cleaning, sterilization and their associated validation costs. Pumpling has become a very sensitive pharmaceutical component to enable proper operation of disposable process system, especially in centrifuge, filtrations, chromatography steps, fluid transfer lines, and filling operations. Popular pharmaceutical pumps include tube pumps, piston pumps, centrifugal pumps, diaphragm pumps, quattroflow pums, peristaltic pumps, etc.
Single-use pumps feature replaceable pump chambers, which eliminate the need for time-consuming cleaning of the pumps between batches and eliminates the risk of cross-contamination. They have been used in the biologics manufacturing for transferring shear sensitive intermediates and biological products without damage, ultimately ensuring product quality, safety, efficiency and reliability. There are various types of Single Use pumps in the market such as Peristaltic, Centrifugal, Piston and Positive Displacement pumps, so it is crucial to select the most suitable pump for the application.
Cole-Parmer has a broad range of pumps and fluid system components for laboratory, analytical, and industrial process applications includes peristaltic pumps, positive displacement pumps, metering pumps, centrifugal pumps, and more. It also offers the tubing, fittings, filters, regulators, flowmeters, and gauges to complete fluid handling system. Product categories are Air Compressors, Centrifugal Pumps, Centrifugal Separators, Drum and Hand Pumps, Filling Pumps, Gear Pumps, Metering Pumps, Microfluidic Pumps, Motors, Peristaltic Pumps, Positive Displacement Pumps, Pump Parts and Accessories, Submersible Pumps and Sump Pumps, Transfer Pumps, Vacuum Pumps
ReadyToProcess Pump 25 is used for applications such as perfusion culture, medium handling, and addition of feed, acid or base to the culture. ReadyToProcess Pump 25 is a peristaltic unit incorporating two roller pumps for feed, harvest, and pH control. Flow rate is regulated by weight feedback from the scale and is controlled by automatic adjustments of the pump speed or Manual adjustment.
PendoTECH Magma Advanced Pumping Systems
Magma Advanced Pumping Systems include a range of air diaphragm pumps for liquid transfer operations, especially when low shear sanitary/sterile pumping. A range of pump sizes are available with both cylindrical designs and long-life dome diaphragms with single use options.
Watson-Marlow Peristaltic Pump
Watson-Marlow offers peristaltic dosing and metering pumps that are simple to install and easy to use. These pumps have no seals, valves or moving parts in the flow path, therefore reduced the risk of clogging, leaking or contamination. Watson-Marlow Peristaltic Pumps peristaltic pumps include Qdos peristaltic metering pumps, 500 series process pumps , 600 series mid flow process pumps, 700 series transfer pumps, 100 series laboratory pumps, 200 series multi channel cassette pumps, 300 series laboratory tube pumps, OEM Product Range cased and panel mount pumps,, and 800 series high flow hygienic pumps. Watson-Marlow also offers Masosin Process Pumps, and Bredel Hose Pumps and Elements.
MasoSine Process Pump
MasoSine pumps are reliable displacement pumps for sanitary and industrial applications. The exclusive sinusoidal rotor overcomes the limitations of conventional rotary lobe pumps to produce powerful suction, low shear and very low pulsation. New Certa Pump has Superior viscous handling with Low shear and virtually no pulsation. Featured products include MasoSine pump for industrial applications and SPS industrial pumps. In addition MR high flow sanitary pumps have low shear transfer; EcoSine sanitary pumps can perform bidirectional operation.
Levitronix® Hygienic Pumps and PuraLev® Single-Use Life Science Pump Series
LEVITRONIX® hygienic pumps are unique centrifugal pumps that are based on the principles of magnetic levitation, the pump’s impeller is suspended contact-free inside a sealed casing and is driven by the magnetic field of the motor. The dead-zone-free pump design and the smooth plastic surfaces aid in avoiding deposition in the pump, and no narrow gaps exist. Levitronix’ pump controllers achieve closed-loop flow control without the need of additional controller hardware.Levitronix® bearingless pump systems come with variable speed control so that the pump speed can be selected to optimally mach operating point. Levitronix pumps include BPS pump series, PuraLev® multiple-use pump series, and PuraLev® sinlge-use pump series.
Spectrum Labs offer Pumps and Pump Head including permeate pumps, pump heads and mounting plates for life Science Applications.
Pump Solutions Group (PSG) Dover Pump Technologies
PSGDover Provide Pump Technologies include Hydraulic Pump, Mechanical Pump, Fertilizer & Chemgation Pumps, Solenoid Pump, Peristaltic Hose Pump. Abaque® Series pumps feature a seal-less design that eliminates leaks and product contamination, and have the ability to run dry continuously without adversely affecting the pump’s performance. The Almatec Diaphragm ALMATEC BIOCOR air-operated double diaphragm pump series is especially designed for sterile applications. In addition, Wilden’s Saniflo and BioPharm air-operated double-diaphragm pumps are made with passivated stainless steel components and come in various sizes and finishes. Quattroflow Single-Use pumps are equipped with a product wetted plastic (polypropylene) pump chamber that can be replaced as a complete unit. They are available in different sizes, and for more information, see Quattroflow Biopharma Brochure
Quattroflow Particle Generation Flyer.
LEWA diaphragm and piston pumps are reciprocating positive displacement pumps that offer the great metering accuracy. Process Pumps, including LEWA triplex, LEWA ecoflow and LEWA plunger pumps, are reliable, durable and energy-efficient pumps in high-pressure process technology. Centrifugal pumps or rotary pumps are distributed from various manufacturers and for many different applications such as the low temperatures, highest viscosities and abrasive fluids.
Waukesha Cherry-Burrell (WCB) Pumps
SPXFLOW and Waukesha Cherry-Burrell Offer Pump Products include Universal 1 and Universal 2 Series Positive Displacement Pumps. The Universal 2 positive displacement pump include advanced sanitation technologies and long life features for biopharma applications: 200 Series Centrifugal Pumps offer users quality, value and high levels of performance. Universal Lobe Series Positive Displacement Pumps are fully CIPable, the lobe pump body offers an alternative to higher priced external circumferential piston Positive Displacement pumps. E-Series Magdrive Centrifugal Pumps are magnetically driven and made specifically for hygienic applications.
SciLog ChemTech™ Intelligent Metering System
The ChemTec™Metering System includes on-board application software and hardware that automates, optimizes and documents high precision metering by weight or volume. The ChemTec™ System is an exclusive software-driven fluid delivery system that automatically regulates feed-rate based on user defined time schedule or feedback from sensors and detectors. Users may choose their own pump head, whether peristaltic, piston, (Watson Marlow, Tandem, Cole-Parmer), rotary lobe (ITT Jabsco), or magnetic gear (Micropump). Flow meters, level sensors. It can also act as a pH controller for pH maintenance or simple end point titration.
Fristam Pumps for Pharmaceutical
Fristam Pumps (Hamburg, Germany) offer pump types include positive displacement pumps, centrifugal pumps, and high pressure centrifugal pumps. The FKL positive displacement pump (Ultraclean PD Pump) is built for high performance and complete reliability. It is designed to provide consistent flow and gentle handling of shear sensitive products. Fristam WFI Centrifugal Pumps and CIP-return pumps are for clean, reliable, and efficient processing.
Alfa Laval Pharmaceutical Production
Alfa Lavel (Lund, Sweden) offers a range of centrifugal pumps and rotary lobe pumps with hygienic design for the pharmaceutical industry. This includes centrifugal and positive displacement pumps, as well as liquid ring pumps for liquids containing air or gas. More product categories include Centrifugal pumps, Circumferential piston pumps, and Rotary lobe pumps.
The Finesse SmartPump series has been designed to meet high precision liquid delivery requirements in upstream and downstream bioprocess applications. By combining pump heads from Watson Marlow® with Finesse electronic SmartBoards, the SmartPump series offer precise control of process dosing, feeding, product transfer / harvest, buffer mixing (gradient or step) or general liquid management.
CPI supplies NaoPump technologies. The proprietary piston pump systems offer high performance compared to peristaltic, diaphragm and syringes pumps. CPI also has an extensive range of pump technology from design to installation. Products include HMD Sealless Mag Drive Pumps, Ansimag Lined Magnetic Pumps, MILTON ROY Dosing , CRANE Depa AODD, CRANE Elro Peristaltic, MASTERFLEX Bio Peristaltic, POMAC Hygenic Centrifugal, POMAC Rotary Lobe, NASH Liquid Ring ELMO RIETSCHLE Dry Run, ELMO RIETSCHLE Side Channel Blowers, SPP General Water & Utility, Greenpumps (Regenerative), etc.
Quantex single use pump echnology comprises of five components – the housing, rotor, spring barrel, seal and seal cap. See the video and learn how the Quantex pump works.
Terra Universal Vacuum Pumps and Compressors
Terra offers a complete line of vacuum and pressure pumps and compressors for laboratory and cleanroom operations that require clean, quiet performance. Featured products are Laboratory Vacuum Pumps from Welch-ILMVAC. Selection of Vacuum & Pressure Pumps including rotary vane vacuum pumps, diaphragm vacuum pumps and dry roughing pumps for cleanroom and non-corrosive applications. Also see other products such as Pump Accessories and Cleanroom compressors and filters.
U.S. Plastic Corp.® carry a wide variety of pumps from branded manufacturers to transfer liquids. The products include submersible, magnetic drive, diaphragm, and metering pumps among others. Also, the pumps can be manual, air or electrically driven. U.S. Plastic Corp.® also has an excellent selection of pump accessories for biopharmaceutical pump applications.
Holland Sanitary Stainless Sanitary Pumps
Holland offers a broad selection of pumps from multiple manufacturers, featured products include Waukesha Positive rotary pumps, centrifugal pumps, peristaltic pumps, Quattroflow pumps, axiflow twin screw pumps, APV R series Pump, Graco Pneumatic Piston and AOD pumps. Supporting system include Sanitary pump skids and carts, and pump repair products. This innovative Quattroflow pump technology can be found in multi use/permanent cleanable applications or single use applications.
SI Ultrapure supplies Levitronic PuraLev Multi Use Pumps and Levitronix PuraLev Single Use pumps.
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